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2B), indicative of an elevation of GSH export in response to cystine starvation

4.1 Complexity of GB biology Intra-tumoral heterogeneity, which has also been previously described in GB using single-cell RNA-seq profiling ( Redundant signaling pathways in gliomagenesis limit the effectiveness of targeted therapies that focus on a single gene or pathway, even when the tumors complete molecular profile is known

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