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Effect of probiotic supplements on oxidative stress biomarkers in first-episode bipolar disorder patients: a randomized, placebo-controlled trial

Patti AM, Nikolic D, Magan-Fernandez A, Giglio RV, Castellino G, Chianetta R, et al

Main outcomes were early stent occlusion (within 48 hours after eCAS), symptomatic intracranial hemorrhage (sICH), and good functional outcome at 3 months defined as a modified Rankin scale (mRS) 0-2

As a whole, these studies underpin further inquiry into the use of probiotic strategies as preventative and adjunctive dependent modalities for bipolar disorder, whereas further studies in humans are required to ascertain efficacy and achieve protocol optimization

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