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doi:10.1089/acm.2005.11.909

How Tesofensine Works: Mechanism of Action Tesofensine is a triple monoamine reuptake inhibitor (MRI) a rare class of compounds that simultaneously boosts the availability of three key neurotransmitters: dopamine , norepinephrine , and serotonin

The aldehyde products generated from hydroxyl radical action on PUFA are normally neutralized by glutathione conjugation or via aldehyde dehydrogenase activity in mitochondria

Although there is little evidence, they have encouraging results as adjunctive therapy in histamine intolerance mediated by gut