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Increase: Titrate gradually toward 1.52 mg daily as tolerated and aligned with protocol goals

Consider baseline labs for copper and zinc and reassess if symptoms or labs shift

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The unique characteristics of central iron homeostasis and the presence of the BBB also pose therapeutic challenges

A However, other In addition, a The authors of the systematic review recommend against the use of self-administered coffee enemas as a complementary and alternative therapy that people can use for self-care