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Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms

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SCI leads to ROS accumulation in skeletal muscle [40], resulting in oxidative injury, a key contributing factor to skeletal muscle atrophy [41]

Perhaps more importantly for osteoporosis patients, researchers showed that administering additional PEPITEM in animal models of menopause-induced bone loss limited the bone density decline and improved overall bone density