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J Pediatr 165:528533

C.CaramoriG.PerrosF.MengC.GambaryanN.DorfmullerP.et al (2013)

Most practitioners recommend 12-16 week cycles followed by a 2-4 week assessment break

The link between UPS impairment and PD pathogenesis is increasingly clear because in addition to -synuclein, Lewy bodies also contain ubiquitin, parkin and other proteasomal proteins [355-357] (Fig