Focused Nursing Assessment and Diagnostics Subjective Data: Reports of weakness, fatigue, dizziness, and shortness of breath on exertion Headaches or lightheadedness Difficulty concentrating Objective Data: Pallor of skin, nail beds, and mucous membranes Tachycardia, hypotension, and dyspnea Brittle nails, spoon-shaped nails, or glossitis Cold extremities and delayed capillary refill Diagnostic Tests: Complete Blood Count (CBC): Low hemoglobin, hematocrit, and RBC count Iron studies: Low serum iron, ferritin, and transferrin saturation Reticulocyte count: Evaluates bone marrow response Stool guaiac test: Detects occult blood loss Peripheral smear: Assesses RBC morphology Nursing Care Plan #1: Fatigue Related to Decreased Oxygen-Carrying Capacity Nursing Diagnosis: Fatigue related to decreased oxygen-carrying capacity of the blood secondary to low hemoglobin levels, as evidenced by verbal reports of tiredness, inability to perform usual activities, and pallor
Frequency of administration All clinical trial cohorts used once-weekly subcutaneous injection
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6.4 Determination of the burden of senescent cells The burden of senescent cells in the kidney may be a useful index for predicting renal prognosis (Liu et al., 2012)
