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B12 is crucial for the production and maturation of red blood cells

Semaglutide, tirzepatide, and retatrutide produce 15-24% body weight reduction in clinical settings

This safety profile reflects the peptides selectivity by avoiding systemic hormonal disruption, it also avoids the adverse effects associated with broader metabolic interventions

Furthermore, these conditions can also result in the prothrombotic state, proinflammatory state, nonalcoholic fatty liver disease, and reproductive disorders (Cornier et al., 2008)

AOD-9604, as a C-terminal fragment lacking affinity for the growth hormone receptor, avoids these metabolic complications