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Research combining L-arginine with pycnogenol (a plant extract with antioxidant properties) showed more promising results than arginine alone, suggesting that addressing multiple pathwaysNO production and oxidative stressmay be more effective

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Finally, cisplatin is also recognized as substrate by CT2: higher levels of CT2 expression in lung cancer was correlated to increased cellular uptake of cisplatin (Table 1)

Using nuclear magnetic resonance (NMR) spectroscopy, Smeland and colleagues also demonstrated increased levels of norepinephrine and serotonin in the cortex of healthy mice, after 25 days of treatment with acetylcarnitine at a daily dose of approximately 0.5 g/kg body weight [117]

Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress