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(2016) were the first to demonstrate that transplanting fecal matter from PD patients into mice genetically engineered to overexpress alpha-synuclein significantly worsened their motor symptoms compared to mice receiving transplants from healthy human donors

Some abnormal plasma elevations of hemostatic parameters, including factor VIII (Freyburger et al, 1997), von Willebrand factor (van den Berg et al, 1995), fibrinogen (von Eckardstein et al, 1994), thrombomodulin (van den Berg et al, 1995), thrombin/antithrombin III complex and activated protein C (Cattaneo, 1999

In the animal CVS model after SAH, the autophagy pathway was activated in the basilar artery wall after SAH, and CysC-induced autophagy played a beneficial role in preventing SAH-induced CVS (Sun C