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Immunometabolism affects the tumor microenvironment Tumor cells perform aerobic glycolysis under normoxic conditionsa phenomenon known as the Warburg effect

Here, we reveal that the aldehyde derivative of UNC10088 promotes cooperative binding of FBXO22 to NSD2, a histone methyltransferase and oncogenic protein, leading to a cryo-EM structure of the SKP1-CUL1-F-box (SCF)-FBXO22 complex with NSD2

Similar content being viewed by others Introduction EpsteinBarr virus was the first tumorigenic DNA virus that persistently infects human and some additional primate B cells

Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells

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