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VPS33B regulates protein sorting into and maturation of -granule progenitor organelles in mouse megakaryocytes

Although a number of pre-clinical phage display studies show promise for the utility of cancer-targeting peptides [16, 17], clinical data demonstrate the need for further optimisation for translational success in terms of improving receptor affinity, enzyme instability and pharmacokinetics [18, 19]

Schneider CS, Perez JG, Cheng E, Zhang C, Mastorakos P, Hanes J, et al

Identifying the Engine's Faulty Parts Several core biological pathways can get thrown off balance, each one acting like a different kind of engine trouble

[DOI] [PMC free article] [PubMed] [Google Scholar] Lemons J.M., Feng X.J., Bennett B.D., Legesse-Miller A., Johnson E.L., Raitman I., Pollina E.A., Rabitz H.A., Rabinowitz J.D., Coller H.A