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In biochemical and dermal research models, it is utilized to study extracellular matrix remodeling and vascular endothelial growth factor (VEGF) expression

This dual activation cascade induces catastrophic breakdown of alveolar-capillary barrier integrity, manifesting pathologically as alveolar edema, neutrophilic inflammation, and refractory hypoxemia (Jin et al., 2021)

Sepsis Sepsis results from dysfunctional immune responses to infection, leading to life threatening inflammation and organ dysfunction

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