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In the STEP 1 trial, once-weekly semaglutide 2.4 mg plus lifestyle intervention produced about 14.9% mean weight loss at 68 weeks, compared with about 2.4% with placebo

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PCOS is a common chronic health condition affecting up to 10% of all women, and is defined by androgen excess, anovulation and often polycystic ovarian morphology on imaging (Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2004)

Certain banned substance categories are restricted during competition periods but not out-of-competition