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D., Tsuji, P

In vivo experiments further demonstrated that Irisin-loaded bone marrow mesenchymal stem cell-derived exosomes significantly inhibited activation of the YAP/EGR1/ACSL4 signaling pathway in the brains of middle cerebral artery occlusion (MCAO) mice, suppressed ferroptosis and lipid peroxidation, thereby mitigating ischemic brain injury (Fang et al., 2025)

Along with healing GI tract it protects it from inflammation by improving blood flow

doi: 10.1007/s00204-024-03903-2

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