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In pregnancy, a lack of folate can lead to pregnancy loss and neural tube defects, and has also been linked to a higher risk of behavioural disorders such as autism and ADHD

Common experiences may include increase in energy or mental clarity, reduced muscle tension, reduced stiffness, improved mobility and range of motion, a sense of calm, reduced stress, and deep more restful sleep

10.1371/journal.pone.0073866 164 LuengoA.GuiD

doi: 10.3389/fimmu.2017.01452 Pubmed Abstract CrossRef Google Scholar 7 BonazBPicqCSinnigerVMayolJFClarenconD

Similarly, a better ORR trend was also seen in those who developed pyrexia (65% versus 35%