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This copper-dependent form of cell death is known as cuproptosis ( 2+ enters the mitochondrial compartment of cells, FDX1 reduces Cu 2+ to Cu + , resulting in the oligomerization of DLAT protein and the downregulation of Fe-S cluster protein expression

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Clarkson T W Vyas J B, Ballatori N

With respect to liver metabolism, studies have shown that Scrophulariae Radix significantly regulates phospholipid metabolites such as phosphatidylcholine and phosphatidylethanolamine, aiding in restoring lipid metabolism balance and preventing common lipid metabolic disorders in hyperthyroid patients (102)

doi: 10.13406/j.cnki.cyxb.003042 112 LiNLiuL