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In addition, it has been shown that when the ferroptosis inducer imidazole ketone erastin (IKE), SOR and cytoplasmic proton radiation act synergistically, tumor killing is significantly enhanced in mouse xenograft models and human patient-derived lung adenocarcinoma models [199]

S., Hoffman, H

BioMed Res Int 2014:151479

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Residual cells, debris were discarded by centrifugation and CM concentrated with concentricon devices (Millipore, Temecula, CA) with a 3-kDa membrane pore cut-off, which eliminates the residual ALCAR