glutathione stransferase tag S-transferase Glutathione S-Transferase (GST) Fusion Protein

Sturm B, Bistrich U, Schranzhofer M, Sarsero JP, Rauen U, Scheiber-Mojdehkar B, de Groot H, Ioannou P, Petrat F: Friedreich's ataxia, no changes in mitochondrial labile iron in human lymphoblasts and fibroblasts: a decrease in antioxidative capacity

GSH is the primary endogenous antioxidant depleted in PD and NAC promote glutathione homeostasis indirectly by providing cysteine for GSH synthesis

This was often accompanied by enrichment of pro-inflammatory Proteobacteria and depletion of protective phyla such as Verrucomicrobia, indicating a shift toward inflammation and barrier dysfunction (Stolfi et al., 2022)

PubMed Central, Camacho, Antnio, et al

10.1038/mp.2017.171 365 TurnerB