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Exosomes are a subclass of extracellular vesicles of endosomal origin, which are released from the cells for extracellular communication by the transportation of proteins, DNA or RNA (Simpson et al

It plays a role in the angiogenesis and vasculogenesis processes, where it regulates the expression of key molecules on the cell surface to modulate cell adhesion and motility 42

Yuan J, Luo RZ, Fujii S, Wang L, Hu W, Andreeff M , Pan Y, Kadota M, Oshimura M, Sahin AA, Issa JP, Bast RC, Jr, Yu Y

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Final Results of RTOG 0246: A Phase II Study of Selective Surgical Resection for Locoregionally Advanced Esophageal Cancer Treated With Paclitaxel Based Chemoradiation Regimen