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379 Coculture of iPSC-derived -cells with endothelial cells and their integration into a bioengineered vascular system enabled the creation of a functional, sustainable, humanized endocrine organ, with a controlled in vitro insulin-secreting phenotype and effective in vivo function

Concurrently, TMAO activates the ROS-TXNIP-NLRP3 pathway, causing endothelial inflammatory dysfunction and accelerating atherosclerotic plaque formation

The blood samples were immediately placed on ice after collection and was centrifuged within 15 min of collection, as described previously (16)

L-Carnitine (and Acetyl-L-carnitine) supports cellular energy metabolism by helping to transport fatty

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