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While the precise mechanisms by which acupuncture improves conditions related to gastrointestinal motility diseases remain partly understood, both fundamental and clinical research evidence appears to endorse the following processes: acupuncture stimulates somatic and peripheral nerves, which transits an afferent signal to the brain and spinal cord, leading to an increased vagal activity or a reduction in sympathetic efferent output to the digestive system (Figure 2), ultimately enhancing motility [15, 21]