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64 (Suppl.), S71S73 (2015)

R., Fairbrother, A., Baecher-Steppan, L

This conjugation process transforms lipid-soluble toxins into water-soluble compounds that can be safely eliminated through bile and urine, protecting cellular structures from oxidative damage and toxic accumulation

Gaining a mechanistic understanding of the engagement between such compounds and apo(a) enabled us to develop molecules that are selective for apo(a) over plasminogen in humans