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Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome

When the cellular activity promoting ferroptosis significantly exceeds the antioxidant buffering capacity provided by the ferroptosis defense system, there is an excessive accumulation of lipid peroxides on the cell membrane and subsequent membrane rupture, leading to cellular ferroptosis (Stockwell et al., 2020

FIGURE 2 3.1.2 NPs in activating natural killer (NK) cells NK cells are essential for first-line resistance towards infectious pathogens and malignant conditions