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For drug resistance regulation, metabolic reprogramming mediated by SSP activation represents a common mechanism underlying chemoresistance and targeted therapy resistance across pan-cancer

This just-formed superoxide, together with its reduced metabolites, can interact with a great number of different naturally occurring body biomolecules, at least partially leading to the development of many diseases such as cardiovascular disease, cancer, chronic inam- mation, dementia, and amyotrophic lateral sclerosis, among others [ 140 , 141 ]

In: Frontiers in gynecological endocrinology: Volume 3: Ovarian function and reproduction-from needs to possibilities

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The inflammatory phase typically starts within hours post-injury and can last for several days, during which neutrophils and macrophages are recruited to the wound site to clear pathogens and necrotic tissue, while secreting various growth factors and cytokines to initiate repair (Pea and Martin, 2024