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Coupled with the MS database of microorganism, identification and classification of bacterial species with MALDI-TOF MS have been achieved 27,28,29

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Metformin attenuated the progression of OA in an MIA-induced mouse model To further investigate the effect of metformin on OA progression, radiological assessments, histological analyses and plasma assays were conducted to evaluate subchondral bone remodeling, articular cartilage degradation, and inflammation at 8 weeks post-MIA injection