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A meta-analysis study showed that for L-carnitine to have significant effects on FBG levels in patients with diabetes, 2 grams/day should be taken as a supplement for at least 36 weeks, also it is estimated that 2 g of L-carnitine per day is needed for at least 106 weeks to have a significant effect on HbA1c levels (87)

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Consequently, patients often find themselves in a state of functional malnutrition, even if their caloric intake is adequate, because their cellular demand for anti-inflammatory nutrients far exceeds their dietary supply