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GSK-3, glycogen synthase kinase 3

Unsaturated fatty acid moieties of membrane lipids are attacked by free radicals, which leads to a self-replicating chain reaction of non-enzymatic lipid peroxidation that produces malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), isoprostains and other compounds

Radiosensitization by 2-deoxy-D-glucose and 6-aminonicotinamide involves activation of redox sensitive ASK1-JNK/p38MAPK signaling in head and neck cancer cells

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In aquaculture, it is vital for collagen formation in fish bones and skin, supporting normal growth, wound healing, and stress resistance during handling and transport