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This potential interface contains two hydrophobic residues, F897 and L901, and a positively charged residue, R908, that line up on one side of the helix

By selectively disrupting key antioxidant systemssuch as inhibiting glutathione synthesis with buthionine sulfoximine (BSO), blocking thioredoxin reductase with auranofin, or directly targeting NRF2therapies can push cancer cells beyond their limited oxidative buffering capacity

Three transcription factors are encoded by the Myc gene family: c-Myc, L-Myc, and N-Myc

Push the plunger down slowly and steadily until all the medication is injected