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High concentration of H 2 O 2 can produce reactive oxygen species, which potentially causes DNA impairment and propagate cancer [1-3]

Direct comparison revealed significantly higher expression of GABARALP1 , HSP90AA1 , PLOD2 , and UBC in HepG2 ATP7B-KO cells at 6 h, and only GABARALP1 remained elevated at 24 h

There are various types of mutations, including chromosomal, point, frameshift, and expansion mutations

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