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Risks are increased in patients with a personal or family history of substance abuse (including drug or alcohol abuse or addiction) or mental illness (e.g., major depression)

Discussing all available treatment options with a physician is essential to determine the most appropriate plan of care

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Some may do so, but it is usually not recommended by reputable clinicians

High-throughput 16S rRNA gene sequencing reveals alterations of intestinal microbiota in myalgic encephalomyelitis/chronic fatigue syndrome patients