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Although the MT1 and MT2 receptors feature fairly conserved binding pockets for melatonin, they also take distinctive conformational states that modulate ligand selectivity, important for designing subtype-specific therapeutics [39]

[] Genistein binds with the estrogen receptor as a competitive agonist of estradiol on estrogen-sensitive cancer cells in another study of plant estrogens

Ex vivo experiments on human skin organ culture showed a significant reduction in pro-inflammatory cytokine production