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Even if the PCAC votes in favor and the FDA agrees, formal notice-and-comment rulemaking is STILL required, a process that can take a year or more under standard timelines

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In CRC, the reactivation or remodeling of mitochondrial metabolic pathways, particularly oxidative phosphorylation (OXPHOS) and fatty acid oxidation (FAO), is closely associated with key oncogenic processes such as the evasion of apoptosis, the maintenance of cancer stem cell properties, and the regulation of redox homeostasis [5,6,7,8]