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CYP1A homologues also metabolize AFB 1 to produce the detoxified metabolite AFM 1 , whereas CYP3A enzymes - P450 III AY and in the fetal liver P450 III A6 , produce another detoxified metabolite, aflatoxin Q 1 (AFQ 1 ), the major metabolite of AFB 1 (Figure 2)

[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Allegretti J.R., Kassam Z., Carrellas M., Mullish B.H., Marchesi J.R., Pechlivanis A., Smith M., Gerardin Y., Timberlake S., Pratt D.S., Korzenik J.R

Previous data demonstrates how IGF-1 can be an effective option in the treatment of this worldwide increasing condition

Another major benefit of inhaled drug administration is its potential suitability for low-resource settings, in which simpler delivery methods and reduced need for medical infrastructure can be especially valuable