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Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver

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However, the addition of exogenous GSH reduced activities of the PA synthesis-enzymes like arginine decarboxylase (ADC), S-adenosylmethionine decarboxylase (SAMDC), and diamine oxidase (DAO), while increased the activities of polyamine oxidase (PAO) and ornithine decarboxylase (ODC), resulting in reduced levels of PAs such as Spd, Spm and Put

Particularly via NF-B, exacerbates the inflammatory response and accelerates cartilage degradation and the development of degenerative diseases like arthritis (Lepetsos et al., 2019

GABAA receptor-associated protein (GABARAP) induces apoptosis by interacting with DEAD (Asp-Glu-Ala-Asp/His) box polypeptide 47 (DDX 47)