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Premature infants who develop BPD are exposed to supplemental O 2 and show marked evidence of oxidant stress as suggested by elevated glutathione disulfide (GSSG) concentrations

Second, they augment ROS clearance by supplying antioxidant moleculessuch as glutathione secreted by Saccharomyces boulardii (Badr et al., 2021)and by activating endogenous antioxidant systems

Head Neck 24(12):1068-71, 2002

And despite being unplanned, it works remarkably well in building curiosity and recall

Unfortunately, the long-term effects of chemonucleolysis includes lower back pain partially due to depolymerization of the overall NP structure and loss of water content