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Many scholars have conducted a lot of research on regulating the stressful effects of heavy metals on plant growth, and the common ones are regulating the bioefficacy of soil cadmium through the application of different sulphur-containing compounds (Gypsum, Magnesium sulphate, Sodium sulphate, Monosulphur, etc.) [5, 6]

The exogenous death receptor pathway is another important route for apoptosis

FIGURE 1 A systematic literature search was performed across the PubMed database for relevant studies published up to June 2025

Our LRP6-proximal hits further include CDK14 which initiates Wnt signaling following activation by membrane-associated cyclin Y 34 (see Introduction), and mitogen-activated kinase 4 (MLK4), a tumor suppressor in -catenin-driven colon cancers 84 (Fig

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