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10.1016/j.reprotox.2010.07.007 37 StergiakouliE.ThaparA.DaveyS

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At least three independent trials were carried out for each nanomaterialssiRNA conjugate being tested

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This result is interesting in two aspects: first, it provides further evidence of increased DNA DSB abundance in motor neurons of Wobbler mice and confirms the overexpression of H2ax at the mRNA level and increased H2ax fluorescence signal intensity in spinal cord sections of Wobbler mice