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Moreover, treatment of CC mice with NA rescued NAD + levels in skeletal muscle, improved muscle function, and increased Oxphos complexes expression, yet NA treatment had no effect on mitochondrial respiration 248

It presents a significant diagnostic and therapeutic challenge due to its varied clinical manifestations and overlap with other liver diseases, as, for instance, primary biliary cholangitis or primary sclerosing cholangitis

Esophageal disorders including gastroesophageal reflux disease (GERD), esophagitis, and esophageal ulceration may benefit from BPC-157's demonstrated effects on esophageal sphincter function and mucosal healing in animal models

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