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With high glucose availability, estrogen upregulates glycolysis and suppresses the TCA cycle, whereas, under glucose deprivation conditions, it inhibits glycolysis and promotes the TCA cycle by activating pyruvate dehydrogenase (PDH) to ensure cellular survival [41]

Rohatgi PR, Swisher SG , Correa AM, Wu TT, Liao Z, Komaki R, Walsh G, Vaporciyan A, Lynch PM, Rice DC, Roth JA, Ajani JA

Liberman AC, Budziski ML, Sokn C, Gobbini RP, Steininger A, Arzt E

10.3389/fphar.2019.00252 222 RegelmannW

Peripheral cytokines are not influenced by the type of surgical approach for non-small cell lung cancer by four weeks postoperatively