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However, since approved treatments for MS work by reducing immune system activity or blocking entry of immune cells into the CNS, thus reducing relapse rate and severity of attacks, but they do not repair immune-mediated damage to the myelin sheaths surrounding axons, drug repurposing or development of new treatments to promote myelin repair and neuronal protection is desirable

GLP-1 agonists (semaglutide, tirzepatide) reduce appetite and slow gastric emptying to create caloric deficits, while AOD-9604 and 5-Amino-1MQ directly enhance fat mobilisation and oxidation without affecting satiety signalling

Physical interventions: We encourage our patients to seek therapy in various forms, such as chiropractic adjustments, massage, ultrasound, physical therapy, shockwave therapy, cold laser or acupuncture, to name a few

A responsible plan improves outcomes and reduces preventable complications

When it comes to clinical aspects of knee OA assessment, MRI and ultrasound each has its distinct advantages, as shown in the following table: Treatment Options for Knee Osteoarthritis Conventional treatment for knee OA centers on pain management, typically with topical and oral non-steroidal anti-inflammatory drugs (NSAIDs)