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They can reduce a wide variety of protein disulfides since the active site surface of these enzymes can undergo chaperone-like conformational changes to accommodate different proteins [90]

N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs

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For patients who do not respond or experience significant fluctuations, alternative approaches such as plasma exchange, combination therapy, or immunosuppressive medications may be considered