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QUR increases PNO2 expression in brain cells, macrophages, neurons, and striatal astrocytes, not only at the mRNA but also at the protein level (Boesch-Saadatmandi et al., 2009)

Personally, I know through genetic testing that I have the SNP (single nucleotide polymorphism) rs1050450(C;T) on my GPX1 gene which reduces my glutathione peroxidase activity and therefore my ability to combat oxidative stress