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It can make it harder to know which compound is helping, which one is causing side effects, and how the overall protocol should be adjusted

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Unlike hepatocellular carcinoma, ferroptosis is largely governed by system Xc heterodimeric transporter (SLC7A11 and SLC3A2) inhibition and basal ROS stress [148], glioblastoma exhibits a GPX4-dependent survival phenotype, particularly in GSCs

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