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Transmission electron microscopy and western blot in TMEM41B KO hepatocytes revealed decreased MAM structure and levels of PSD1 and PEMT, two enzymes critical for mitochondrial-associated ER membrane (MAM) phospholipid (PL) synthesis

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The impact of GPS on cellular processes extends to the modulation of proteins critical for cell cycle regulation, including cyclin-dependent kinases (CDKs) and cyclins