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Consequently, while Bax/Bcl2 offers an attractive mechanistic lens to understand how combined nutritionalmechanical strategies might simultaneously protect muscle, modulate tumor behaviour, and mitigate therapyrelated tissue damage, the translational reliability of these findings should currently be regarded as moderate, and they should primarily guide the design of future hypothesisdriven human trials rather than immediate clinical practice

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He encourages the public to go beyond advertising hype and pursue meaningful clinical evidence

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