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An in vivo study performed by Obrosova (2009) demonstrated that administration of a PARP inhibitor counteract small sensory nerve fiber dysfunction and degeneration

Inhibition of key regulators of 2D cell locomotion such as actin polymerization, cell-matrix adhesion, and myosin contractility fail to block confined migration of MDA-MB-231 breast cancer cells [153], suggesting the existence of alternative mechanisms facilitating their movement

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