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Ethics declarations Competing interests The authors declare no conflict of interest

Published data suggests up to 2.6% incidence of B12 deficiency within a year of treatment, and this figure climbs in patients who have used these medications long term or combined them with very low calorie diets (3)

AMP Kinase (AMPK): AMPK, a key energy-sensing kinase, modulates the activity of glutamine-PRPP amidotransferase to ensure that nucleotide synthesis is in sync with cellular energy status

Is It Safe to Stop Taking Gabapentin Abruptly

Therefore, varying drugs, including antidiabetics, antioxidants, lipid-lowering drugs, probiotics, and anti-platelets, which might have potential beneficial effects, have been continuously investigated in patients with CLD [8-15]