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Study participants and biospecimen collection For prospective sample collection, patients undergoing colonoscopy or sigmoidoscopy for standard of care indications were screened for study eligibility

Evidence suggests MRS is inadequate, however, and often yields inconsistent results across studies

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Prior research has demonstrated that STEAP3, functioning as a metal reductase, transforms Fe3+ into Fe2+ and contributes to iron homeostasis in tissues and cells

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