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In the early stages of tumour invasion and metastasis, neutrophils can release neutrophil extracellular traps (NETs), which include DNA, tissue proteins and other substances

For the isASO-ID SILAC-MS/MS experiments in panel a-f, detected proteins were colored according to their biological function as P-body component (gold), paraspeckle protein (red) and the annotated GO terms DNA binding (orange) and RNA binding (blue)

The opening of mPTP is often regarded as a hallmark of cell death, especially when the cell is subjected to severe injury or stress

Guidelines for local anesthetic use in dermatologic surgery